Primary Pulmonary Synovial Sarcoma Showing a Prolonged Survival with Multimodality Therapy

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Author(s)

    • Ogino Hirokazu
    • Department of Respiratory Medicine and Rheumatology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Yamago Taito
    • Department of Respiratory Medicine and Rheumatology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Toyoda Yuko
    • Department of Respiratory Medicine and Rheumatology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Bando Yoshimi
    • Division of Pathology, Tokushima University Hospital, Japan
    • Nishioka Yasuhiko
    • Department of Respiratory Medicine and Rheumatology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Hanibuchi Masaki
    • Department of Respiratory Medicine and Rheumatology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Takizawa Hiromitsu
    • Department of Thoracic, Endocrine Surgery and Oncology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Sakiyama Shoji
    • Department of Thoracic, Endocrine Surgery and Oncology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Sumitomo Hiroyuki
    • Department of Thoracic, Endocrine Surgery and Oncology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Iwamoto Seiji
    • Department of Radiology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Ikushima Hitoshi
    • Department of Radiology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Nakajima Kohei
    • Department of Neurosurgery, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan
    • Nagahiro Shinji
    • Department of Neurosurgery, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan

Abstract

A 54-year-old man was referred to our hospital due to a mass shadow noted on a chest X-ray. Thoracoscopic lobectomy yielded a diagnosis of primary pulmonary synovial sarcoma according to the histology and <i>SYT-SSX1</i> gene analyses. Five months after the thoracic surgery, he developed brain metastasis; therefore, we performed resection of the brain metastatic focus followed by radiotherapy. As a local recurrence in the thoracic cavity concurrently emerged, systemic chemotherapy was also administered. These observations indicated that a multidisciplinary approach may be useful against primary pulmonary synovial sarcoma, although there is presently no established therapeutic strategy due to its rarity and highly aggressive nature.<br>

Journal

  • Internal Medicine

    Internal Medicine 55(4), 381-387, 2016

    The Japanese Society of Internal Medicine

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