がん検診を契機に発見された膣原発末梢性T細胞リンパ腫  [in Japanese] Primary peripheral T-cell lymphoma of the vagina incidentally found at cervical cancer screening  [in Japanese]

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Author(s)

    • 磯部 玲 ISOBE Rei
    • 長野県厚生連佐久総合病院 内科 Department of Internal Medicine, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 三石 俊美 MITUISHI Toshimi
    • 長野県厚生連佐久総合病院 内科 Department of Internal Medicine, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 表 真由子 [他] OMOTE Mayuko
    • 長野県厚生連佐久総合病院 内科 Department of Internal Medicine, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 森 勇一 MORI Yuichi
    • 長野県厚生連佐久総合病院 内科 Department of Internal Medicine, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 井田 耕一 IDA Koichi
    • 長野県厚生連佐久総合病院 産婦人科 Department of Obstetrics Gynecology, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 小口 治 OGUCHI Osamu
    • 長野県厚生連佐久総合病院 産婦人科 Department of Obstetrics Gynecology, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 仲井 育子 NAKAI Ikuko
    • 長野県厚生連佐久総合病院 産婦人科 Department of Obstetrics Gynecology, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare
    • 小口 正彦 OGUCHI Masahiko
    • 長野県厚生連佐久総合病院 放射線科 Department of Radiation Oncology, Saku Central Hospital, Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare

Abstract

症例は50歳女性。婦人科がん検診で膣壁腫瘤を指摘され,当院を紹介された。造影CT・MRIで,膣壁は高度に肥厚し96 mmに達する腫瘤を形成していた。PET/CTでも同部位に一致して集積を認めたが,他部位には集積を認めなかった。経膣壁的腫瘤生検にて末梢性T細胞リンパ腫,非特定型(PTCL-NOS)と診断した。内視鏡検査では膀胱,直腸への浸潤は確認されなかったが,MRIでは直腸壁への浸潤が示唆された。Biweekly THP-COP療法6コース施行後病変は消失し,局所放射線照射(39.6 Gy)が追加された。膣原発のPTCL-NOSは稀であり報告する。

A 50-year-old woman was referred to our hospital because a mass lesion had been palpable through the vaginal wall during a cervical cancer screening examination. A contrast-enhanced computed tomography (CT) scan and magnetic resonance imaging (MRI) revealed marked thickening of the vaginal wall, constituting a mass 96 mm in diameter. Abnormal FDG uptake was observed in the vaginal mass, but no other lesions were detected by positron emission tomography (PET/CT). A transvaginal biopsy from the tumor revealed peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Although endoscopic examinations revealed no signs of infiltration in either the bladder or the rectum, the MRI findings suggested invasion into the adjacent rectal wall. She achieved complete remission after six courses of biweekly THP-COP therapy, to which field radiation (39.6 Gy) was added. PTCL of the vagina is rare and this case therefore merits description in the literature.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 57(1), 20-24, 2016

    The Japanese Society of Hematology

Codes

  • NII Article ID (NAID)
    130005125842
  • NII NACSIS-CAT ID (NCID)
    AN00252940
  • Text Lang
    JPN
  • ISSN
    0485-1439
  • NDL Article ID
    027094341
  • NDL Call No.
    Z19-295
  • Data Source
    NDL  J-STAGE 
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