A case of paroxysmal sympathetic storm after acute disseminated encephalomyelitis and hypoxic encephalopathy responding to clonidine hydrochloride
-
- Shimmura Mitsunori
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
-
- Kawamura Nobutoshi
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
-
- Tateishi Takahisa
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
-
- Shigeto Hiroshi
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
-
- Murai Hiroyuki
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
-
- Kira Jun-ichi
- Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University
Bibliographic Information
- Other Title
-
- 塩酸クロニジンが有効であった急性散在性脳脊髄炎および低酸素脳症後のparoxysmal sympathetic stormの1例
Search this article
Abstract
We report the case of a 17-year-old woman with paroxysmal sympathetic storm (PSS), which was successfully treated with clonidine hydrochloride. The patient was hospitalized for acute disseminated encephalomyelitis in June 2006. Dysphagia led to severe aspiration pneumonia in September 2006, and she suffered cardiopulmonary arrest. She survived but had severe brain damage, with her brain MRI showing diffuse hypoxic encephalopathy. From October 2006, she had several episodes of profound tachypnea (> 60/min), tachycardia (160 to 170 beats/min), hypertension (> 140 mmHg), hyperthermia (39°C), and decerebrate posturing. During the attacks, the levels of catecholamines in the patient’s blood and urine were markedly elevated. Accordingly, a diagnosis of PSS associated with hypoxic encephalopathy was made. Her PSS clearly improved after the administration of clonidine hydrochloride (900 μg/day). This case suggests that clonidine hydrochloride, an α2 blocker, may be one therapeutic option for PSS.
Journal
-
- Rinsho Shinkeigaku
-
Rinsho Shinkeigaku 56 (2), 108-111, 2016
Societas Neurologica Japonica