Drug-susceptibility of isolates of Brachyspira hyodysenteriae isolated from colonic mucosal specimens of pigs collected from slaughter houses in Japan in 2009

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  • KAJIWARA Keita
    United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, 3–5–8 Fuchu, Tokyo 183–8509, Japan School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan
  • KOZAWA Midori
    School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan
  • KANAZAWA Takuya
    School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan
  • UETSUKA Kouji
    School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan
  • NAKAJIMA Hiromi
    School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan
  • ADACHI Yoshikazu
    School of Agriculture, Ibaraki University, 3–21–1 Ami, Ibaraki 300–0393, Japan

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  • Drug-susceptibility of isolates of <i>Brachyspira hyodysenteriae</i> isolated from colonic mucosal specimens of pigs collected from slaughter houses in Japan in 2009

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Twenty nine isolates identified as Brachyspira hyodysenteriae were most susceptible to carbadox and metronidazole, whereas they were resistant to macrolides. The isolates showed intermediate susceptibility to tiamulin, lincomycin, penicillin G, ampicillin, chloramphenicol, tetracycline, enrofloxacin and valnemulin, with MIC50 values ranging from 0.39 to 3.13.

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