vWF 分子機構による血小板粘着のバイオレオロジー

• 谷下 一夫

  早稲田大学 ナノ理工学研究機構

書誌事項

タイトル別名

• Biorheology of platelet adhesion with vWF molecular mechanism

抄録

The platelet adhesion is initiated by the interaction between the A1 domain of von Willebrand factor (vWF) and the leucine-rich repeats of glycoprotein Ibα (GPIbα) under the condition of high shear rate. Many studies have been made for the biorhoelogical and molecular aspects of the adhesion process, and this shear dependent mechanism has been revealed gradually. This brief review roughly covers the recent progress of the study of platelet adhesion under the condition of high shear rate.

収録刊行物

• Journal of Japanese Society of Biorheology

  Journal of Japanese Society of Biorheology 28 (1), 3-6, 2014

  特定非営利活動法人 日本バイオレオロジー学会

キーワード

• platelet
• adhesion
• high shear rate
• von Willebrand factor (vWF)
• A1 domain
• glycoprotein Ibα (GPIbα)
• measurement of adhesion force

詳細情報

• CRID: 1390282680457243392
• NII論文ID: 130005142793
• DOI: 10.11262/jpnbr.28.1_3
• ISSN: 21865663
• ISSN: 09134778
• Web Site: https://search.jamas.or.jp/link/ui/2014325893
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可