Simple Size-controlled Preparation of Micro-/nano-sized Fullerene C<sub>60</sub> Particles using Different Chain-length Diaminoalkane Compounds
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- MUTOH Mami
- Graduate School of Dental Medicine,
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- ABE Shigeaki
- Graduate School of Dental Medicine,
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- NAKAYAMA Katsutoshi
- Division of Materials Chemistry, Graduate School of Engineering, Hokkaido University, Sapporo, Japan
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- YOSHIZAWA Saori
- Graduate School of Dental Medicine,
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- NAKAMURA Mariko
- School of Health Science, Kyushu University of Health and Welfare, Nobeoka, Japan
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- KUSAKA Teruo
- Graduate School of Dental Medicine,
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- YOSHIDA Yasuhiro
- Graduate School of Dental Medicine,
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- IIDA junichiro
- Graduate School of Dental Medicine,
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- TAKADA Tomoya
- Department of Applied Chemistry and Bioscience, Chitose Institute of Science and Technology, Chitose, Japan
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Abstract
In this study, we demonstrated a simple preparation of size-controlled fullerene C60 micro-/nano- particles. The fullerene particles were prepared through the reaction of fullerene C60 with a diaminoalkane. The resultant particles were spherical and their size depended on the alkyl chain length of the diaminoalkane compounds. In addition, we successfully modified the hydrophilic surface of the fullerene nanoparticles using succinic anhydrite. The obtained hydrophilic particles are dispersible in water, and the resultant solution is injectable into animals. This surface modification, which involves the introduction of -COOH groups onto the particle surface, may allow the nanoparticle to be tethered to functional moieties such as fluorescence dyes, oligosaccharides, antibodies and drugs. Thus, these simple preparations can widely extend the application of these particles in various fields particularly in biology.
Journal
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- Nano Biomedicine
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Nano Biomedicine 7 (2), 87-92, 2015
Nano Biomedical Society
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Details 詳細情報について
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- CRID
- 1390001205344239744
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- NII Article ID
- 130005150633
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- ISSN
- 21854734
- 18835198
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- Text Lang
- en
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed