Recent Views of Proton-Selective Permeation: Lesson from Voltage-Gated Proton Channel

• OKAMURA Yasushi

  Graduate School of Medicine, Osaka University

Bibliographic Information

Other Title

• 電位依存性プロトンチャネルにおけるプロトン透過の機構
• デンイ イソンセイ プロトンチャネル ニ オケル プロトン トウカ ノ キコウ
• 測定の名人

Abstract

Protons play critical roles in many biological events, including energy metabolism, neuronal signals, cell motility and cancer progression. Voltage-gated proton channel, VSOP/Hv1, has the voltage-sensor domain which has dual roles of voltage sensing and proton permeation. This review discusses proton-selective permeation through the voltage sensor domain of VSOP/Hv1.

Journal

• Seibutsu Butsuri

  Seibutsu Butsuri 56 (3), 154-158, 2016

  The Biophysical Society of Japan General Incorporated Association

Keywords

• proton
• gate
• ion channel
• membrane potential
• water wire
• salt bridge
• deprotonation

Details

• CRID: 1390001206534245888
• NII Article ID: 130005153075
• NII Article ID: 130005121653
• NII Book ID: AN00129693
• DOI: 10.2142/biophys.56.154
• DOI: 10.2142/biophys.56.001
• ISSN: 13474219
• ISSN: 05824052
• NDL BIB ID: 027477188
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027477188
• Web Site: https://www.jstage.jst.go.jp/article/biophys/56/3/56_154/_pdf
• Web Site: https://www.jstage.jst.go.jp/article/biophys/56/1/56_001/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2016353173
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed