In Situ Cell Surface Modification for Surface-enhanced Raman Analysis of Cell Membrane

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Author(s)

    • Okamoto Yukihiro
    • Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
    • Ikeda Takumi
    • Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
    • Suga Keishi
    • Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
    • Umakoshi Hiroshi
    • Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University

Abstract

We report in situ cell surface modification for surface-enhanced Raman analysis of cell membrane. Our method can produce silver metals on cell membrane via the formation of complex of silver ions and membrane proteins, followed by reduction of silver ion. Formed silver metals generated surface-enhanced Raman signal and enabled the high-sensitive detection of Raman signal from the cell membrane. Thus, our method is expected to be applied for cell membrane analysis.

Journal

  • Chemistry Letters

    Chemistry Letters 45(6), 622-624, 2016

    The Chemical Society of Japan

Codes

  • NII Article ID (NAID)
    130005155041
  • Text Lang
    ENG
  • ISSN
    0366-7022
  • Data Source
    J-STAGE 
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