In vitro assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization
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- MIYAJIMA Hiroyuki
- Department of Biomaterials Science, Osaka University Graduate School of Dentistry
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- ISHIMOTO Takuya
- Department of Materials Science and Engineering, Osaka University Graduate School of Engineering
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- MA Sai
- Department of Prosthodontics, School of Stomatology, Fourth Military Medical University
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- CHEN Jihua
- Department of Prosthodontics, School of Stomatology, Fourth Military Medical University
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- NAKANO Takayoshi
- Department of Materials Science and Engineering, Osaka University Graduate School of Engineering
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- IMAZATO Satoshi
- Department of Biomaterials Science, Osaka University Graduate School of Dentistry
書誌事項
- タイトル別名
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- <i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization
抄録
The purpose of this study was to evaluate the ability of a calcium-fluoroaluminosilicate glass-based desensitizer (Nanoseal) to protect against root demineralization in vitro. Nanoseal was applied to human root dentin, which was immersed in acidic buffer for 72 h, or exposed to pH cycling by immersing in distilled water or mineralizing solution for 24 h intermediately during 48 h-acid attack. Demineralization was evaluated by μ-CT, and mineral loss (ML) and lesion depth (LD) were determined from mineral density profiles. ML and LD in all treatment groups were significantly smaller compared with control. The Nanoseal-treated group with pH cycling using mineralizing solution had the lowest ML and LD. Analysis using an EPMA demonstrated calcium and phosphorous were incorporated into the superficial layer of specimens in the Nanoseal-treated groups, suggesting Nanoseal modified the dentin surface, making it resistant to demineralization. Application of Nanoseal is an effective method for protecting root from demineralization.
収録刊行物
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- Dental Materials Journal
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Dental Materials Journal 35 (3), 399-407, 2016
日本歯科理工学会