<i>In vitro</i> assessment of a calcium-fluoroaluminosilicate glass-based desensitizer for the prevention of root surface demineralization

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Author(s)

    • MIYAJIMA Hiroyuki
    • Department of Biomaterials Science, Osaka University Graduate School of Dentistry
    • ISHIMOTO Takuya
    • Department of Materials Science and Engineering, Osaka University Graduate School of Engineering
    • MA Sai
    • Department of Prosthodontics, School of Stomatology, Fourth Military Medical University
    • CHEN Jihua
    • Department of Prosthodontics, School of Stomatology, Fourth Military Medical University
    • NAKANO Takayoshi
    • Department of Materials Science and Engineering, Osaka University Graduate School of Engineering
    • IMAZATO Satoshi
    • Department of Biomaterials Science, Osaka University Graduate School of Dentistry

Abstract

The purpose of this study was to evaluate the ability of a calcium-fluoroaluminosilicate glass-based desensitizer (Nanoseal) to protect against root demineralization <i>in vitro</i>. Nanoseal was applied to human root dentin, which was immersed in acidic buffer for 72 h, or exposed to pH cycling by immersing in distilled water or mineralizing solution for 24 h intermediately during 48 h-acid attack. Demineralization was evaluated by μ-CT, and mineral loss (ML) and lesion depth (LD) were determined from mineral density profiles. ML and LD in all treatment groups were significantly smaller compared with control. The Nanoseal-treated group with pH cycling using mineralizing solution had the lowest ML and LD. Analysis using an EPMA demonstrated calcium and phosphorous were incorporated into the superficial layer of specimens in the Nanoseal-treated groups, suggesting Nanoseal modified the dentin surface, making it resistant to demineralization. Application of Nanoseal is an effective method for protecting root from demineralization.

Journal

  • Dental Materials Journal

    Dental Materials Journal 35(3), 399-407, 2016

    The Japanese Society for Dental Materials and Devices

Codes

  • NII Article ID (NAID)
    130005155202
  • Text Lang
    ENG
  • ISSN
    0287-4547
  • Data Source
    J-STAGE 
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