特発性後天性全身性無汗症/減汗性コリン性蕁麻疹7例における減汗状態およびステロイドパルス療法による発汗回復の部位別検討  [in Japanese] Studies on Hidrotic Condition and Sweating Recovery after Corticosteroid-pulse Therapy in Seven Patients with Acquired Idiopathic Generalized Anhidrosis/ Anhidrotic or Hypohidrotic Cholinergic Urticarial  [in Japanese]

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Abstract

発汗低下を主訴に最近当科を受診し,特発性後天性全身性無汗症または減汗性コリン性蕁麻疹と診断した7例について,温熱発汗テスト,アセチルコリン皮内反応テスト,組織学的検討を行い,ステロイドパルス療法を行った.全例男性で体表面積の63%以上が減汗であり,6例が点状膨疹を伴っていた.無汗部位は下腿に,低汗部位は上肢・体幹に主に認められた.治療後,全例で発汗回復部位が現れ,同低汗部位に一致して点状膨疹が出現した.減汗性コリン性蕁麻疹は無汗部位ではなく低汗部位に生じ易いことを裏づけた.

To investigate the hidrotic condition and sweat recovery after corticosteroid pulse therapy, we performed hyperthermia sweating test, acetylcholine dermal injection test, and histopathological examinations on seven patients with acquired idiopathic generalized anhidrosis (AIGA)/anhidrotic or hypohidrotic cholinergic urticaria. All the patients were male, and decreased sweating was found on the more than 80% of their body surfaces. Six of 7 patients had cholinergic urticaria. The predilection sites of anhidrosis were mainly the lower extremities, while the hypohidrotic areas included the upper limbs and trunk. After treatment with corticosteroid pulse therapy, sweating recovery was observed in all patients, and cholinergic urticaria appeared in the sweating recovery sites. Our study showed that cholinergic urticaria appears in the hypohidrotic sites but not in the anhidrotic areas.

Journal

  • The Japanese Journal of Dermatology

    The Japanese Journal of Dermatology 126(7), 1263-1271, 2016

    Japanese Dermatological Association

Codes

  • NII Article ID (NAID)
    130005158174
  • NII NACSIS-CAT ID (NCID)
    AN00196602
  • Text Lang
    JPN
  • ISSN
    0021-499X
  • NDL Article ID
    027432903
  • NDL Call No.
    Z19-202
  • Data Source
    NDL  J-STAGE 
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