Substituent Effect at the C4-Position of 1,3a,6a-Triazapentalene

• Nakayama Atsushi

  Graduate School of Pharmaceutical Science, Tokushima University

• Nishio Satoshi

  Graduate School of Pharmaceutical Science, Tokushima University

• Otani Akira

  Graduate School of Pharmaceutical Science, Tokushima University

• Mera Akane

  Graduate School of Pharmaceutical Science, Tokushima University

• Osawa Ayumi

  Graduate School of Chemical Science and Engineering, Hokkaido University

• Tanino Keiji

  Department of Chemistry, Faculty of Science, 
Hokkaido University

• Namba Kosuke

  Graduate School of Pharmaceutical Science, Tokushima University

Abstract

Various 2,4-disubstituted-1,3a,6a-triazapentalenes possessing methyl and phenyl groups at the C4-position were synthesized. Fluorescence observation of the synthetic 4-methyl- and 4-phenyl-1,3a,6a-triazapentalenes revealed that the introduction of a substituent at the C4-position allowed a long-wavelength shift of the fluorescence maximum. Furthermore, the phenyl group at the C4-position was found to induce a substantial increase in the extinction coefficient value.

Journal

• Chemical and Pharmaceutical Bulletin

  Chemical and Pharmaceutical Bulletin 64 (7), 830-837, 2016

  The Pharmaceutical Society of Japan

Keywords

• 1,3a,6a-triazapentalene
• substituent effect
• longer-wavelength shift
• 4-methyl-1,3a,6a-triazapentalene
• 4-phenyl-1,3a,6a-triazapentalene

Details

• CRID: 1390001204178797056
• NII Article ID: 130005160032
• NII Book ID: AA00602100
• DOI: 10.1248/cpb.c16-00196
• ISSN: 13475223
• ISSN: 00092363
• NDL BIB ID: 027451551
• PubMed: 27373639
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027451551
• Web Site: https://www.jstage.jst.go.jp/article/cpb/64/7/64_c16-00196/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed