Bioactive Secondary Metabolites with Unique Aromatic and Heterocyclic Structures Obtained from Terrestrial Actinomycetes Species

• Abdelfattah Mohamed S.

  Graduate School of Pharmaceutical Sciences, Chiba University Chemistry Department, Faculty of Science, 
Helwan University

• Arai Midori A.

  Graduate School of Pharmaceutical Sciences, Chiba University

• Ishibashi Masami

  Graduate School of Pharmaceutical Sciences, Chiba University

Abstract

Natural products from actinomycetes are important and valuable sources for drug discovery and the development of biological tools. The present review describes our recent study on the isolation of new natural products mainly possessing heterocyclic and aromatic ring structures with biological effects on cancer-related cellular pathways such as tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) and Wnt signaling.

Journal

• Chemical and Pharmaceutical Bulletin

  Chemical and Pharmaceutical Bulletin 64 (7), 668-675, 2016

  The Pharmaceutical Society of Japan

Keywords

• actinomycete
• isobenzofuran
• phenazine
• acridine
• naphthoquinone
• signaling pathway

Details

• CRID: 1390001204177406848
• NII Article ID: 130005160043
• NII Book ID: AA00602100
• DOI: 10.1248/cpb.c16-00038
• ISSN: 13475223
• ISSN: 00092363
• NDL BIB ID: 027451359
• PubMed: 26936155
• Web Site: http://id.ndl.go.jp/bib/027451359
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027451359
• Web Site: https://www.jstage.jst.go.jp/article/cpb/64/7/64_c16-00038/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2017038248
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed