Reaction of 2a,8b-Dihydrobenzo[<i>b</i>]cyclobute[<i>d</i>]pyran-3-ones with Dimethylsulfoxonium Methylide
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Using dimethylsulfoxonium methylide as the methylene transfer reagent, 2a,8b-dihydrobenzo[<i>b</i>]cyclobute[<i>d</i>]pyran-3-ones were converted into 2,2′-biphenol derivatives as major products and dihydrodibenzofurans as minor products. The reaction mechanism was extrapolated from a deuteration experiment with CD<sub>2</sub>=S(O)(CD<sub>3</sub>)<sub>2</sub>.
- Chemical and Pharmaceutical Bulletin
Chemical and Pharmaceutical Bulletin 64(7), 1056-1061, 2016
The Pharmaceutical Society of Japan