Relations between polysomnographic characteristics and mortality in cardiac disease patients with sleep apnea syndrome

• MATSUI SHOJIRO

• WATANABE EIICHI

• SUZUKI YASUYUKI

• NOMURA TAISHIN

• KIYONO KEN

Bibliographic Information

Other Title

• 睡眠時無呼吸症候群を合併した心疾患患者における終夜睡眠ポリグラフデータの特性と予後との関係

Abstract

Sleep disordered breathing (SDB) has been identified as mortality risk factor in patients with cardiovascular disease. Although the severity of SDB is quantified primarily by the apnea-hypopnea index (AHI), the average number of apneas and hypopneas per hour of sleep, it is not clear whether the AHI is a reliable index to evaluate an increased mortality risk associated with SDB in cardiovascular disease patients. To address this problem, we analyzed polysomnogram (PSG) data including nasal flow and pulse oximetry (SpO₂) level signals, and studied the association between characteristics of the PSG data and mortality in cardiovascular disease patients (n=112) with central sleep apnea due to Cheyne-Stokes breathing pattern. Compared to airflow-related parameters such as AHI, SpO₂ level-related parameters, such as cumulative time rate with desaturation episodes, was stronger predictors of all-cause mortality. This result suggests that characteristics of SpO₂ level drop related with SDB provide more important information to predict the mortality risk in cardiovascular disease patients than conventional AHI.

Journal

• Transactions of Japanese Society for Medical and Biological Engineering

  Transactions of Japanese Society for Medical and Biological Engineering 53 (Supplement), S223_02-S223_02, 2015

  Japanese Society for Medical and Biological Engineering

Details

• CRID: 1390282680242745984
• NII Article ID: 130005163565
• DOI: 10.11239/jsmbe.53.s223_02
• ISSN: 18814379
• ISSN: 1347443X
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed