光線力学的診断において脳腫瘍からの蛍光を強調表示するための画像処理システム  [in Japanese] A video processing system to highlight fluorescence from brain tumors in photodynamic diagnosis  [in Japanese]

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Abstract

In the photodynamic diagnosis of brain surgery, neurosurgeons visually verify fluorescence signals from a brain tumor. Therefore, they can detect strong fluorescence signals but not weak ones. The purpose of this research is to build a new imaging system to highlight such weak fluorescence signals during brain tumor resection.<br>The proposed system comprised a light source for the fluorescence excitation, a video camera to record fluorescence, and a PC for image processing.<br>We recorded 630-nm fluorescence from a brain tumor as a 24-bit color-depth image video and evaluated the RGB components in each pixel of the fluorescence. The R-component of this fluorescence had pixel values of 4-10 for the fluorescence and values of 1-3 for noise. The fluorescence was invisible on the recorded video and was only included in the R-component. To highlight weak fluorescence, we wrote a program to sum any capture images to improve the SNR and to emphasize the R-components of the images. Applying the image-processing program to a fluorescence video, we were able to observe the weak fluorescence on the PC monitor.<br>We confirmed that the proposed system that we built can highlight weak fluorescence from a brain tumor.

Journal

  • Transactions of Japanese Society for Medical and Biological Engineering

    Transactions of Japanese Society for Medical and Biological Engineering 53(Supplement), S215_01-S215_01, 2015

    Japanese Society for Medical and Biological Engineering

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