Future perspective of strategic non-thermal plasma therapy for cancer treatment

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Author(s)

    • Kajiyama Hiroaki
    • Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine
    • Utsumi Fumi
    • Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine
    • Nakamura Kae
    • Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine
    • Tanaka Hiromasa
    • Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine|Plasma Nanotechnology Research Center, Nagoya University
    • Toyokuni Shinya
    • Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine
    • Hori Masaru
    • Plasma Nanotechnology Research Center, Nagoya University
    • Kikkawa Fumitaka
    • Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine

Abstract

<p>The therapeutic effects of non-thermal plasma are expected in the medical fields, including hemostasis, vascularization, prevention of organ adhesion, and cell proliferation. Cancer is an internal enemy arising from normal tissue in the body. The prognosis of metastatic and recurrent cancers is still poor despite advances in medicine. To apply non-thermal plasma in cancer treatment is now on going. The mechanism of the proliferation-inhibitory effect of plasma is reactive nitrogen oxide species/reactive oxygen species production in cells. There are a number of problems to be overcome, such as existence of intrinsic reactive oxygen species/reactive nitrogen species scavengers and the shallow infiltration of plasma on tumor surface. The current reviews makes referral to the study results of plasma therapy clarified so far, the possibility of its application in the future.</p>

Journal

  • Journal of Clinical Biochemistry and Nutrition

    Journal of Clinical Biochemistry and Nutrition 60(1), 33-38, 2017

    SOCIETY FOR FREE RADICAL RESEARCH JAPAN

Codes

  • NII Article ID (NAID)
    130005188914
  • Text Lang
    ENG
  • ISSN
    0912-0009
  • Data Source
    J-STAGE 
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