Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
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- Koyama Noriko
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Tomoda Koichi
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Matsuda Masayuki
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Fujita Yukio
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Yamamoto Yoshifumi
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Hontsu Shigeto
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Tasaki Masato
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Yoshikawa Masanori
- The Second Department of Internal Medicine, Nara Medical University, Japan
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- Kimura Hiroshi
- The Second Department of Internal Medicine, Nara Medical University, Japan
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Abstract
<p>We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions. </p>
Journal
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- Internal Medicine
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Internal Medicine 55 (24), 3635-3639, 2016
The Japanese Society of Internal Medicine