移植臓器におけるC型肝炎の再発
書誌事項
- タイトル別名
-
- Hepatitis C recurrence after orthotopic liver transplantation
この論文をさがす
抄録
<p>Hepatitis C recurrence after orthotopic liver transplantation (OLT) has been accepted as a major problem after OLT. Recent progress in hepatitis C virus (HCV) treatment with the use of direct acting antivirals (DAA) has almost resolved this major issue, as 95-100% of non-OLT hepatitis C patients in Japan reach a sustained viral response (SVR). However, the SVR rate among post-OLT hepatitis C patients in the United States and Europe is reported to be 90% and 10% of these patients require an additional approach. As the pathogenesis of hepatitis C involves immunological responses, post OLT hepatitis C exhibits complex phenomena with immune regulating agents including prednisolone and calcineurin inhibitors and HLA-mismatch in the recipient immune system and the donor liver. The pathogenesis and the recent progress in post-OLT hepatitis C are described in this chapter.</p>
収録刊行物
-
- 移植
-
移植 51 (2-3), 092-099, 2016
一般社団法人 日本移植学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282680488162304
-
- NII論文ID
- 130005260490
-
- ISSN
- 21880034
- 05787947
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可