Effects of High-frequency Electromagnetic Wave Stimulation on Bone Repair in Rat Calvaria Defects
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- SATO Takahito
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- SUGAYA Tsutomu
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- KUDO Megumi
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- NAKATANI Mitsunori
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- MAEDA Nagako
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- KAWANAMI Masamitsu
- Department of Periodontology and Endodontology, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan
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- TOMINAGA Toshihiko
- Tominaga Dental Clinic, Naruto, Japan
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<p>High-frequency electromagnetic wave stimulation induces proliferation and differentiation of osteoblasts. The aim of the study is to histopathologically evaluate the effects of high-frequency electromagnetic waves on bone formation.</p><p>Bone defects with a diameter of 4.8 mm were created on the left and right sides of the calvarias of Wistar rats. The active electrode was placed in the left defect and high-frequency electromagnetic stimulus was applied for 1 s and repeated five times. This was performed twice a week for 2 weeks. The right defects were not stimulated (control group). After 8 weeks, histological specimens were prepared by hematoxylin and eosin (HE) staining, and the rate of bone formation was measured.</p><p>The rate of bone formation was significantly larger in the experimental group than in the control group. These results indicate that high-frequency electromagnetic wave stimulation enhances bone formation in rat calvarial defects.</p>
収録刊行物
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- Journal of Oral Tissue Engineering
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Journal of Oral Tissue Engineering 14 (1), 59-64, 2016
日本再生歯科医学会
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詳細情報 詳細情報について
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- CRID
- 1390282680201044736
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- NII論文ID
- 130005277140
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- ISSN
- 18800823
- 13489623
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可