Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots

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  • OGIHARA Yusuke
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University ImPACT Research Center for Advanced Nanobiodevices, Nagoya University
  • YUKAWA Hiroshi
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University ImPACT Research Center for Advanced Nanobiodevices, Nagoya University
  • ONOSHIMA Daisuke
    ImPACT Research Center for Advanced Nanobiodevices, Nagoya University Institute of Innovation for Future Society, Nagoya University
  • BABA Yoshinobu
    Department of Applied Chemistry, Graduate School of Engineering, Nagoya University ImPACT Research Center for Advanced Nanobiodevices, Nagoya University Institute of Innovation for Future Society, Nagoya University Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) College of Pharmacy, Kaohsiung Medical University

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We investigated the transduction function of a cationic dextran hydroxypropyltrimethyl ammonium chloride-coated magnetic iron oxide nanoparticle (TMADM-03) for transducing quantum dots (QDs) into adipose tissue-derived stem cells (ASCs). As a result, the fluorescence intensity of ASCs labeled with QDs using TMADM-03 was much higher than that of QDs only labeling. These data suggest that TMADM-03 can be useful as a transduction agent for QDs in stem-cell imaging.

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  • Analytical Sciences

    Analytical Sciences 33 (2), 143-146, 2017

    社団法人 日本分析化学会

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