<b>IMMUNOHISTOCHEMICAL DEMONSTRATION OF S-100 PROTEIN IN THE ENDOTHELIAL CELLS OF BLOOD VESSELS IN THE PIG AND </b><b>CATTLE </b>

• IWANAGA TOSHIHIKO

  Department of Anatomy, Niigata University School of Medicine

• FUJITA TSUNEO

  Department of Anatomy, Niigata University School of Medicine

• TAKAHASHI YASUO

  Department of Neuropharmacology, Brain Research Institute, Niigata University

• ISOBE TOSHIAKI

  Department of Chemistry, Faculty of Science, Tokyo Metropolitan University

抄録

The present study deals with immunohistochemical localization of S-100 protein in the blood vessels of the pig and cattle. Immunoreactivity for S-100 protein was selectively seen in the endothelial cells of arteries, but not in those of veins. The immunoreactivity was also found in the endothelial cells of blood capillaries; the endothelial cells of continuous (non-fenestrated) type showed a moderate to intense immunoreactivity, while those of fenestrated type were immunonegative. Immunostaining using antisera specific to α- or β-subunit of S-100 protein revealed that the endothelial immunoreactivity was due to the β-subunit. The present study suggests that S-100 protein in the endothelial cells may be involved in the mechanism of transcytosis like in fat cells which also contains S-100 protein.

収録刊行物

• Biomedical Research

  Biomedical Research 8 (5), 329-334, 1987

  バイオメディカルリサーチプレス

キーワード

• General Biochemistry, Genetics and Molecular Biology
• General Medicine

詳細情報

• CRID: 1390282679878622720
• NII論文ID: 130005320679
• DOI: 10.2220/biomedres.8.329
• ISSN: 1880313X
• ISSN: 03886107
• Web Site: https://www.jstage.jst.go.jp/article/biomedres/8/5/8_329/_pdf
• 本文言語コード: en
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