Prevalence of Renal Dysfunction among Evacuees and Non-evacuees after the Great East Earthquake: Results from the Fukushima Health Management Survey

• Satoh Hiroaki

  Department of Diabetology, Endocrinology, and Metabolism, Fukushima Medical University, Japan Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan

• Ohira Tetsuya

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Epidemiology, Fukushima Medical University, Japan

• Nagai Masato

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Epidemiology, Fukushima Medical University, Japan

• Hosoya Mitsuaki

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Pediatrics, Fukushima Medical University, Japan

• Sakai Akira

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Radiation Life Sciences, Fukushima Medical University, Japan

• Watanabe Tsuyoshi

  Department of Diabetology, Endocrinology, and Metabolism, Fukushima Medical University, Japan Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan

• Ohtsuru Akira

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Radiation Health Management, Fukushima Medical University, Japan

• Kawasaki Yukihiko

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Pediatrics, Fukushima Medical University, Japan

• Suzuki Hitoshi

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Cardiology and Hematology, Fukushima Medical University, Japan

• Takahashi Atsushi

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Gastroenterology and Rheumatology, Fukushima Medical University, Japan

• Kobashi Gen

  Department of Public Health, Dokkyo Medical University, Japan

• Ozasa Kotaro

  Department of Epidemiology, Radiation Effects Research Foundation, Japan

• Yasumura Seiji

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Department of Public Health, Fukushima Medical University, Japan

• Yamashita Shunichi

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Japan and Atomic Bomb Disease Institute, Nagasaki University, Japan

• Kamiya Kenji

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan

• Abe Masafumi

  Radiation Medical Science Center for the Fukushima Health Management Survey, Fukushima Medical University, Japan

Abstract

Objective We conducted the present study to evaluate the prevalence of chronic kidney disease (CKD) and CKD complications among evacuees and non-evacuees after the Great East Japan Earthquake and Fukushima Daiichi nuclear disaster. Methods Twenty-seven thousand and eighty-eight subjects who were living near the Fukushima Daiichi Nuclear Power Plant in Fukushima Prefecture in Japan, aged ≥40 years by the Heath Care Insures, were included in the analyses. Metabolic factors were compared between the evacuees and non-evacuees stratified by the eGFR and proteinuria grades. Results The prevalence of CKD with a low eGFR (<60 mL/min/1.73 m²) and proteinuria were 21.59% and 1.85%, respectively. The risk of CKD complications was classified into four grades according to the eGFR and proteinuria grades. The prevalence of diabetes, hypertension, and dyslipidemia were significantly higher in the very high risk group than in the low risk group. The prevalence of diabetes and dyslipidemia were significantly higher in evacuees than in non-evacuees in only the low risk group. However, a multivariate logistic regression analysis showed that evacuation was not significantly associated with the risk of a low eGFR or proteinuria. Conclusion This study did not reach the definitive conclusion that evacuation elevated the risk of CKD complication, although evacuation might lead to increased CKD complications in the future. We believe that this information is important for follow-up and lifestyle change recommendations for evacuees.

Journal

• Internal Medicine

  Internal Medicine 55 (18), 2563-2569, 2016

  The Japanese Society of Internal Medicine

Keywords

• chronic kidney disease
• Great East Earthquake
• Fukushima Daiichi Nuclear Power Plant accident
• Fukushima Health Management Survey

Details

• CRID: 1390001204875219328
• NII Article ID: 130005414819
• DOI: 10.2169/internalmedicine.55.7023
• ISSN: 13497235
• ISSN: 09182918
• PubMed: 27629948
• Web Site: https://www.jstage.jst.go.jp/article/internalmedicine/55/18/55_55.7023/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2017191495
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed