Eosinophil polyunsaturated fatty acid metabolism and its potential control of inﬂammation and allergy
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Polyunsaturated fatty acids (PUFAs) exhibit a range of biological effects, many of which are mediated through the formation and actions of their bioactive metabolites. It is well appreciated that dietary PUFA balance affects inﬂammation and/or allergic diseases, and recent advances in liquid chromatography tandem mass spectrometry (LC-MS/MS)-based mediator lipidomics have revealed a potential link between PUFA metabolism and biological phenotypes. This review presents insights into the emerging roles of eosinophil PUFA metabolism in controlling inﬂammatory responses and its potential involvement in allergy control.
- Allergology International
Allergology International 65(Supplement.1), 2-5, 2016
Japanese Society of Allergology