Current Topics in Deep Brain Stimulation for Parkinson Disease

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Author(s)

    • UMEMURA Atsushi
    • Department of Research and Therapeutics for Movement Disorders, Juntendo University Graduate School of Medicine|Department of Neurosurgery, Juntendo University Graduate School of Medicine
    • HATTORI Nobutaka
    • Department of Neurology, Juntendo University Graduate School of Medicine
    • ARAI Hajime
    • Department of Neurosurgery, Juntendo University Graduate School of Medicine
    • OYAMA Genko
    • Department of Neurology, Juntendo University Graduate School of Medicine
    • SHIMO Yasushi
    • Department of Research and Therapeutics for Movement Disorders, Juntendo University Graduate School of Medicine|Department of Neurology, Juntendo University Graduate School of Medicine
    • NAKAJIMA Madoka
    • Department of Neurosurgery, Juntendo University Graduate School of Medicine
    • NAKAJIMA Asuka
    • Department of Neurology, Juntendo University Graduate School of Medicine
    • JO Takayuki
    • Department of Neurology, Juntendo University Graduate School of Medicine
    • SEKIMOTO Satoko
    • Department of Neurology, Juntendo University Graduate School of Medicine
    • ITO Masanobu
    • Department of Psychiatry, Juntendo University Graduate School of Medicine
    • MITSUHASHI Takumi
    • Department of Neurosurgery, Juntendo University Graduate School of Medicine

Abstract

There is a long history of surgical treatment for Parkinson disease (PD). After pioneering trials and errors, the current primary surgical treatment for PD is deep brain stimulation (DBS). DBS is a promising treatment option for patients with medically refractory PD. However, there are still many problems and controversies associated with DBS. In this review, we discuss current issues in DBS for PD, including patient selection, clinical outcomes, complications, target selection, long-term outcomes, management of axial symptoms, timing of surgery, surgical procedures, cost-effectiveness, and new technology.

Journal

  • Neurologia medico-chirurgica

    Neurologia medico-chirurgica 56(10), 613-625, 2016

    The Japan Neurosurgical Society

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