SRD Young Investigator Award 2015 : Poultry genetic resource conservation using primordial germ cells
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- NAKAMURA Yoshiaki
- Division of Germ Cell Biology, National Institute for Basic Biology, National Institute of Natural Sciences, Aichi 444-8787, Japan Research Fellow of Japan Society for the Promotion of Science, Tokyo 102-0083, Japan
書誌事項
- タイトル別名
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- Poultry genetic resource conservation using primordial germ cells
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抄録
<p> The majority of poultry genetic resources are maintained in situ in living populations. However, in situ conservation of poultry genetic resources always carries the risk of loss owing to pathogen outbreaks, genetic problems, breeding cessation, or natural disasters. Cryobanking of germplasm in birds has been limited to the use of semen, preventing conservation of the W chromosome and mitochondrial DNA. A further challenge is posed by the structure of avian eggs, which restricts the cryopreservation of ova and fertilized embryos, a technique widely used for mammalian species. By using a unique biological property and accessibility of avian primordial germ cells (PGCs), precursor cells for gametes, which temporally circulate in the vasculature during early development, an avian PGC transplantation technique has been established. To date, several techniques for PGC manipulation including purification, cryopreservation, depletion, and long-term culture have been developed in chickens. PGC transplantation combined with recent advanced PGC manipulation techniques have enabled ex situ conservation of poultry genetic resources in their complete form. Here, the updated technologies for avian PGC manipulation are introduced, and then the concept of a poultry PGC-bank is proposed by considering the biological properties of avian PGCs.</p>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 62 (5), 431-437, 2016
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001206335213056
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- NII論文ID
- 130005431257
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- NII書誌ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 027662003
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- PubMed
- 27210834
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可