Perspectives for Individualized Diagnosis and Treatment Plans for Psoriasis Based on Molecular Genetics

DOI 1 Citations
  • Muto Masahiko
    Department of Dermatology and Biomolecular Recognition, Yamaguchi University School of Medicine
  • Yamaguchi Michiya
    Department of Dermatology and Biomolecular Recognition, Yamaguchi University School of Medicine
  • Yoshikawa Yoshiaki
    Department of Dermatology and Biomolecular Recognition, Yamaguchi University School of Medicine

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Other Title
  • 分子解剖による乾癬の個性診断と治療設計

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Abstract

Psoriasis vulgaris (PV) is a multifactorial skin disorder caused by the concerted action of multiple genetic and environmental factors. Although the strong association between PV and HLA-Cw6 has been well known, HLA-Cw6 itself is unlikely to be a psoriasis susceptibility gene. As a result of the recent progress in molecular genetics, great advances have been reported. In this article, we describe the recent advances in the search for psoriasis susceptibility genes including our current studies and discuss the possibilities of a tailor-made medicine for psoriasis.

Journal

  • Hifu no kagaku

    Hifu no kagaku 3 (5), 518-522, 2004

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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