A case of pediatric mandibular osteonecrosis caused by leakage of arsenic trioxide

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  • ARIOKA Masaki
    Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University
  • SASAKI Masanori
    Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University
  • ISHII Kotaro
    Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University
  • KANAMOTO Masaki
    Department of Dentistry and Oral and Maxillofacial Surgery, Osumi-Kanoya Hospital
  • YAMASHIRO Takahiro
    Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University
  • MORI Yoshihide
    Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University

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Other Title
  • 亜ヒ酸漏洩が原因と考えられた小児下顎骨壊死の1例
  • アヒサン ロウエイ ガ ゲンイン ト カンガエラレタ ショウニ カガクコツ エシ ノ 1レイ

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Abstract

<p>Arsenic trioxide used to be used as an effective endodontic treatment. However, domestic production of arsenic trioxide for mortal pulpectomy was discontinued in 2005, because it is a toxic agent that has the risk of injuring periodontal tissues. We report a case of mandibular osteonecrosis caused by leakage of arsenic trioxide in a child after 2005. The patient was a 6-year-old boy who presented with swelling of the right buccal region, after arsenic trioxide had been used for mortal pulpectomy in the mandibular right second primary molar. The condition was diagnosed as mandibular osteonecrosis. The mandibular right first primary molar and mandibular right second permanent premolar were extracted, and a sequestrectomy was performed with the patient under local anesthesia. We still should consider that leakage of pulp devitalizing agents can cause osteonecrosis.</p>

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