Multiple Kaposi’s sarcoma occurring in oral region: report of a case
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- Noguchi Kazuma
- Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine
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- Kawabe Mutsuki
- Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine
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- Yamanegi Koji
- Department of Pathology, Hyogo College of Medicine
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- Takaoka Kazuki
- Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine
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- Kishimoto Hiromitsu
- Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine
Bibliographic Information
- Other Title
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- 全身および口腔内に多発したカポジ肉腫の1例
Abstract
Kaposi’s sarcoma (KS) is a malignant tumor and is one of the major complications of patients with AIDS, but is rare in Japan. We report a case of AIDS-associated multiple KS of the oral region on the basis of clinical and pathological findings. The patient was a 32-year-old male who had been suffering from a gingival neoplasm-like mass of the incisor region of the maxilla. Intraoral findings showed multiple lesions in this patient. He was diagnosed with AIDS based on data of HIV-RNA: 180,000 copies/ml and CD4: 27/μl. Therefore, the patient’s oral lesion was suspected to be oral KS. A histopathological examination of a gingival biopsy specimen showed typical findings of KS. Furthermore, we confirmed the presence of human herpesvirus (HHV)-8 in this case by immunohistochemistry. Combination anti-retroviral therapy (ART) and liposomal doxorubicin was administered and the patient achieved complete remission (CR) for 3 years.
Journal
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- Journal of Japanese Society of Oral Oncology
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Journal of Japanese Society of Oral Oncology 29 (1), 15-21, 2017
Japanese Society of Oral Oncology
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Details 詳細情報について
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- CRID
- 1390282679322865792
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- NII Article ID
- 130005465149
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- ISSN
- 18844995
- 09155988
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed
