Tumor Affinity Photosensitizers for Photodynamic Therapy

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  • Kataoka Hiromi
    Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences
  • Hayashi Noriyuki
    Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences
  • Tanaka Mamoru
    Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences
  • Kubota Eiji
    Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences
  • Yano Shigenobu
    Graduate School of Materials Science, Nara Institute of Science and Technology
  • Joh Takashi
    Departments of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences

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Other Title
  • PDTに用いられる腫瘍親和性光感受性物質

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Abstract

<p>Antitumor effects of photodynamic therapy (PDT) depend on the tumor selectivity of photosensitizers, inducibility of reactive oxygen species and radiation efficiency. In Japan, the first generation Porfimer sodium and the second generation Talaporfin sodium have been authorized by insurance and recently, the authorized cancer types targeted by PDT are increasing. In the laboratory, the study of the third generation photosensitizers advances and the development of more effective and lower invasiveness photosensitizers is expected. We summarized the characteristics and future prospects of development research of photosensitizers for PDT.</p>

Journal

  • Nippon Laser Igakkaishi

    Nippon Laser Igakkaishi 36 (2), 159-165, 2015

    Japan Society for Laser Surgery and Medicine

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