食品添加物粒子が腸内細菌叢に与える影響  [in Japanese] Nano Particle as Artificial Food Additive Influence to Intestinal Bacterial Flora  [in Japanese]

Access this Article

Search this Article

Author(s)

    • 徳本 勇人 Tokumoto Hayato
    • 大阪府立大学 大学院工学研究科 物質・化学系専攻 Department of Chemical Engineering, Osaka Prefecture University
    • 野村 俊之 Nomura Toshiyuki
    • 大阪府立大学 大学院工学研究科 物質・化学系専攻 Department of Chemical Engineering, Osaka Prefecture University
    • 星 英之 Hoshi Hideyuki
    • 大阪府立大学 大学院人間社会システム研究科 現代システム科学専攻 Graduate School of Humanities and Sustainable System Sciences, Osaka Prefecture University
    • 新居 靖崇 Nii Yasutaka
    • 大阪府立大学 大学院工学研究科 物質・化学系専攻 Department of Chemical Engineering, Osaka Prefecture University
    • 大谷 俊晴 Ootani Toshiharu
    • 大阪府立大学 大学院工学研究科 物質・化学系専攻 Department of Chemical Engineering, Osaka Prefecture University
    • 野本 健太 Nomoto Kenta
    • 大阪府立大学 大学院工学研究科 物質・化学系専攻 Department of Chemical Engineering, Osaka Prefecture University

Abstract

<p>Particles of additives that are ingested along with food can either adhere to the intestinal microflora or be absorbed, and these may possibly lead to illnesses caused by changes in the microflora composition. Barely 1% of Fe<sub>2</sub>O<sub>3</sub> particles dissolve in acids present in the stomach. In addition, the direct administration of Fe<sub>2</sub>O<sub>3</sub> particles into the stomach with a probe showed no adverse health effects. However, mixing Fe<sub>2</sub>O<sub>3</sub> particles of a smaller diameter into food and orally administering the dose over a period of more than 2 weeks encouraged the multiplication of the diarrhea-causing <i>Clostridium</i> family amongst intestinal flora, indicating the cause of the diarrhea outbreak. On the other hand, multiplication of the <i>Clostridium</i> species was suppressed by the multiplication of another family within the intestinal flora, namely <i>Lactobacillus</i>. It was confirmed that by analyzing the formation of fermentation products such as hydrogen, acetic acid, and lactic acid, symptoms of diarrhea caused by the alteration of intestinal microflora composition spontaneously recovered.</p>

Journal

  • Journal of the Society of Powder Technology, Japan

    Journal of the Society of Powder Technology, Japan 54(3), 172-177, 2017

    The Society of Powder Technology, Japan

Codes

  • NII Article ID (NAID)
    130005606222
  • NII NACSIS-CAT ID (NCID)
    AN00222757
  • Text Lang
    JPN
  • ISSN
    0386-6157
  • NDL Article ID
    028049544
  • NDL Call No.
    Z17-38
  • Data Source
    NDL  J-STAGE 
Page Top