Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis

• Mizutani Kazuki

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Hara Masahiko

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Ishikawa Hirotoshi

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Nishimura Shinsuke

  Department of Cardiovascular Surgery, Osaka City University Graduate School of Medicine

• Ito Asahiro

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Iwata Shinichi

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Takahashi Yosuke

  Department of Cardiovascular Surgery, Osaka City University Graduate School of Medicine

• Sugioka Kenichi

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

• Murakami Takashi

  Department of Cardiovascular Surgery, Osaka City University Graduate School of Medicine

• Shibata Toshihiko

  Department of Cardiovascular Surgery, Osaka City University Graduate School of Medicine

• Yoshiyama Minoru

  Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine

Abstract

Background:Balloon aortic valvuloplasty (BAV) is resurging as a bridge treatment in patients with severe aortic stenosis (AS) with a dissemination of transcatheter aortic valve implantation. However, the significantly high periprocedural mortality and complication rates still limit the indications of BAV. Further efforts are needed to improve the safety and efficacy of BAV. Methods and Results:We retrospectively investigated the safety and efficacy of simultaneous biplane mode of 3-dimensional transesophageal echocardiography (biplane-TEE) guided antegrade transseptal multiple-inflation BAV, with gradual upsizing of the balloon, by enrolling 20 consecutive AS patients who underwent BAV. The median age was 83 years, and there were 6 male patients (30.0%). The clinical frailty scale was 4, and the Society of Thoracic Surgeon score was 14.5%. The balloon was inflated at a median of 18 times, which improved the mean aortic valve pressure gradient from 43.0 to 15.2 mmHg (P<0.001). We safely performed BAV in all patients, without periprocedural death or symptomatic stroke, although asymptomatic stroke was detected in 8 patients (42.1%) on diffusion-weighted magnetic resonance imaging. Kaplan-Meier estimates showed that the survival rate was 84.0% and cardiovascular death-free survival was 88.9% at 1-year. Conclusions:Biplane-TEE guided antegrade multiple-inflation BAV might have the potential to improve periprocedural survival without increasing complications, compared with conventional retrograde BAV in patients with severe AS.

Journal

• Circulation Journal

  Circulation Journal 81 (5), 748-754, 2017

  The Japanese Circulation Society

Keywords

• Aortic stenosis
• Balloon aortic valvuloplasty
• Biplane transesophageal echocardiography
• Transcatheter aortic valve implantation

Details

• CRID: 1390282680085347584
• NII Article ID: 130005612056
• NII Book ID: AA11591968
• DOI: 10.1253/circj.cj-16-0909
• ISSN: 13474820
• ISSN: 13469843
• NDL BIB ID: 028129724
• PubMed: 28163283
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I028129724
• Web Site: https://www.jstage.jst.go.jp/article/circj/81/5/81_CJ-16-0909/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2017381439
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed