A case of disseminated mucormycosis during induction therapy for acute lymphoblastic leukemia

DOI
  • Waragai Tomoko
    Department of Pediatrics, Fukushima Medical University Department of Pediatric Oncology, Fukushima Medical University
  • Sano Hideki
    Department of Pediatric Oncology, Fukushima Medical University
  • Akaihata Mitsuko
    Department of Pediatrics, Fukushima Medical University Department of Pediatric Oncology, Fukushima Medical University
  • Kobayashi Shogo
    Department of Pediatric Oncology, Fukushima Medical University
  • Mochizuki Kazuhiro
    Department of Pediatric Oncology, Fukushima Medical University
  • Ohara Yoshihiro
    Department of Pediatrics, Fukushima Medical University Department of Pediatric Oncology, Fukushima Medical University
  • Shimizu Hirofumi
    Department of Pediatric Surgery, Fukushima Medical University
  • Ise Kazuya
    Department of Pediatric Surgery, Fukushima Medical University
  • Yamashita Michitoshi
    Department of Pediatric Surgery, Fukushima Medical University
  • Ishii Sho
    Department of Pediatric Surgery, Fukushima Medical University
  • Hosoya Mitsuaki
    Department of Pediatrics, Fukushima Medical University
  • Kikuta Atsushi
    Department of Pediatric Oncology, Fukushima Medical University

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Other Title
  • 急性リンパ性白血病寛解導入療法中に発症した播種性ムーコル症の一例

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Abstract

<p>A 6-year-old boy with acute lymphoblastic leukemia developed disseminated mucormycosis caused by Rhizopus microsporus during induction therapy. Despite the presence of intestinal perforation and the formation of multiple abscesses, surgical resection and intravenous administration of liposomal amphotericin B were effective, and the patient recovered. Because the prognosis of mucormycosis is very poor, early diagnosis and treatment are important. In cases of patients with risk factors for mucormycosis, physicians must consider the possibility of mucormycosis. Moreover, the empirical administration of liposomal amphotericin B could be a good treatment option before a definitive diagnosis of mucormycosis is made.</p>

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