A pediatric case of Autonomously Functioning Thyroid Nodule

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  • Iwamoto Aya
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine
  • Sugahara Kazuma
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine
  • Hirose Yoshinobu
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine
  • Hara Hirotaka
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine
  • Hashimoto Makoto
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine
  • Yamashita Hiroshi
    Department of Otolaryngology, Yamaguchi University Graduate School of Medicine

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Other Title
  • 小児自律性機能性甲状腺結節の一例

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Abstract

 An autonomously functioning thyroid nodule (AFTN) is a thyroid nodule that secretes thyroid hormones without control by thyroid-stimulating hormone. AFTN is rare in Japan, particularly among children. Here we report a case of AFTN in a 14–year-old boy with symptoms of hyperthyroidism. He was referred to our hospital for further examination of a neck swelling and hyperthyroidism. Examination revealed two thyroid nodules. A small nodule in the right lobe of the thyroid, which showed weak accumulation of Na123I on thyroid scintigraphy, and a second massive nodule in the left lobe which showed strong accumulation of Na123I. First, we treated the hyperthyroidism with medication. Next, we opted for surgical resection of the left lobe including the larger nodule, because that was thought to be the main cause of his symptoms. After surgery, the features of hyperthyroidism resolved and the clinical course was favorable. However, the remaining nodule in the right lobe might continue to grow and become autonomous in the future. Thus, the patient will require long-term follow-up.

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