A Current-Integration-Based CMOS Amperometric Sensor with 1024 × 1024 Bacteria-Sized Microelectrode Array for High-Sensitivity Bacteria Counting

• GAMO Kohei

  Graduate School of Engineering, Nagoya University

• NAKAZATO Kazuo

  Graduate School of Engineering, Nagoya University

• NIITSU Kiichi

  Graduate School of Engineering, Nagoya University JST

抄録

CMOS amperometric sensors with a microelectrode array offer great potential for counting bacteria because of their low cost, compact size, and ease of use. This paper presents a current-integration-based CMOS amperometric sensor for high-sensitivity bacteria counting. It has a current integrator for noise reduction and reportedly the most large-scale microelectrode array (1024 × 1024). This proposed sensor can count the number of bacteria ranging from a single cell to approximately a million cells. A prototype chip was fabricated using two-poly three-metal (2P3M) 0.6-µm standard CMOS technology. A 7.6 × 7.1-mm² chip operates from a 5V supply at 1.9mA. In addition, by using the prototype chip, we performed electrochemical measurement and partial 2D imaging of silicone through constant potential amperometry. The measurement results indicate that the proposed sensor chip was able to accurately readout redox current from the 1024 × 1024 sensor array.

収録刊行物

• IEICE Transactions on Electronics

  IEICE Transactions on Electronics E100.C (6), 602-606, 2017

  一般社団法人 電子情報通信学会

キーワード

• amperometry
• microelectrode array
• electroless plating
• potentiostat

詳細情報

• CRID: 1390282679355745152
• NII論文ID: 130005687753
• DOI: 10.1587/transele.e100.c.602
• ISSN: 17451353
• ISSN: 09168524
• Web Site: https://www.jstage.jst.go.jp/article/transele/E100.C/6/E100.C_602/_pdf
• 本文言語コード: en
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