透析患者における唾液分泌量低下と健康関連Quality of Lifeの関連  [in Japanese] The Association between Hyposalivation and Quality of Life in Dialysis Patients  [in Japanese]

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Author(s)

    • 有永 靖 ARINAGA Yasushi
    • 九州歯科大学地域健康開発歯学分野 Division of Community Oral Health Development, Kyushu Dental University
    • 粟野 秀慈 AWANO Shuji
    • 九州歯科大学クリニカルクラーシップ開発学分野 Division of Clinical Education Development and Research, Kyushu Dental University
    • 伊藤 加代子 ITO Kayoko
    • 新潟大学医歯学総合病院口腔リハビリテーション科 Oral Rehabilitation, Niigata University Medical and Dental Hospital
    • 角田 聡子 KAKUTA Satoko
    • 九州歯科大学地域健康開発歯学分野 Division of Community Oral Health Development, Kyushu Dental University
    • 邵 仁浩 INHO Soh
    • 九州歯科大学地域健康開発歯学分野 Division of Community Oral Health Development, Kyushu Dental University

Abstract

<p> 透析患者では唾液量分泌低下が高頻度で認められる.本横断研究では透析患者における唾液分泌量低下と健康関連quality of life(HRQOL)の関連を,包括的HRQOL尺度MOS Short-Form 36-Item Health Survey(SF-36)を用いて検討した.2008年5月から7月に透析専門病院にて血液透析治療を受けた患者347名中,本研究への同意が得られ,データの揃った212名を対象とした.安静時唾液分泌量が0.1 ml/min 以下かつ刺激時唾液分泌量が1.0 ml/min 以下の者を唾液分泌量低下と定義した.唾液分泌量低下がSF-36のサマリースコア,および下位尺度偏差得点に与える影響について一般線形モデルを用いて評価した.年齢,性別,透析原疾患,透析期間,現病歴,既往歴,body mass index,喫煙状況,飲酒状況を共変量として用いた.唾液分泌量低下と定義された者は103名,全体の48.6%であった.唾液分泌量低下とSF-36の下位尺度偏差得点である身体機能,身体的日常役割機能,全体的健康感,社会生活機能,および身体的側面のQOLサマリースコアとの間に負の関連を認めた(<i>p</i><0.05).透析患者において唾液量分泌低下はHRQOLと関連することが示された.</p>

<p>Hyposalivation is a common oral problem among dialysis patients. This cross-sectional study aimed to investigate the association between hyposalivation and the health-related quality of life (HRQOL) using the MOS Short-Form 36-Item Health Survey (SF-36). Three-hundred and forty-seven patients who received hemodialysis treatment between May 2008 and July 2008 at a specialized hospital were enrolled in the study. Among them, 212 patients who agreed to participate and had complete data sets were entered into the analyses. Those with both a resting salivary flow rate ≤0.1 mL/min and a stimulated salivary flow rate ≤1.0 mL/min were defined as showing hyposalivation. The association of hyposalivation with 8 health domains and 3 summary scores of SF-36 was evaluated using general linear models. The models included adjustments for the age, sex, underlying cause of dialysis, duration of dialysis, comorbidities, body mass index, smoking status, and alcohol use. One-hundred and three patients (48.6% [103/212]) were defined as showing hyposalivation. Hyposalivation was significantly correlated with SF-36 health domains of: physical functioning, role physical, general health, and social functioning; and the summary score: physical component summary (<i>p</i><0.05). The reported findings suggest an independent relationship between hyposalivation and a poor HRQOL among dialysis patients.</p>

Journal

  • JOURNAL OF DENTAL HEALTH

    JOURNAL OF DENTAL HEALTH 67(2), 64-69, 2017

    Japanese Society for Oral Health

Codes

  • NII Article ID (NAID)
    130005697003
  • NII NACSIS-CAT ID (NCID)
    AN00081407
  • Text Lang
    JPN
  • ISSN
    0023-2831
  • NDL Article ID
    028192923
  • NDL Call No.
    Z19-144
  • Data Source
    NDL  J-STAGE 
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