Calcein Leakage Behavior from Vesicles Induced by Protein–Vesicle Interaction: A Study by Surface Pressure–Area Isotherms

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Author(s)

    • Fukuma Saki
    • Department of Environmental Chemistry and Materials, Okayama University
    • Hayashi Keita
    • Department of Chemical Engineering, National Institute of Technology, Nara College
    • Kimura Yukitaka
    • Department of Environmental Chemistry and Materials, Okayama University

Abstract

<p>The release behavior of substrates encapsulated in the vesicle can be controlled by the interaction between the vesicular membrane and the protein. However, its control mechanism is still now unknown. Therefore, the protein–vesicle interaction was investigated by a <i>π</i>–<i>A</i> isotherm. It was clarified that the released amount of encapsulated substrates increased with increasing protein–vesicle interaction. This result leads to the development of drug delivery systems (DDS) and of biosensor technology.</p>

Journal

  • Chemistry Letters

    Chemistry Letters 46(7), 1036-1039, 2017

    The Chemical Society of Japan

Codes

  • NII Article ID (NAID)
    130005709517
  • Text Lang
    ENG
  • ISSN
    0366-7022
  • Data Source
    J-STAGE 
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