Sleep management in a critically ill patient
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- Tsuruta Ryosuke
- Acute & General Medicine, Yamaguchi Graduate School of Medicine
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- Yamamoto Takahiro
- Acute & General Medicine, Yamaguchi Graduate School of Medicine
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- Fujita Motoki
- Acute & General Medicine, Yamaguchi Graduate School of Medicine
Bibliographic Information
- Other Title
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- 重症患者の睡眠管理
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Abstract
Sleep is classified into rapid eye movement (REM) and non-REM (NREM) phases. The centers of sleep and wakefulness are located in the anterior and posterior hypothalamus, respectively. The sleep-wake cycle is controlled by a combination of circadian and homeostatic mechanisms, and regulated by neurotransmitters such as GABA (γ-aminobutyric acid), histamine, orexin, acetylcholine, noradrenaline, serotonin, as well as adenosine. As NREM sleep enhanced by pro-inflammatory and suppressed by anti-inflammatory cytokines, immuno-endocrine system is also involved in the regulation of the sleep. Sleep in critically ill patients characterized by prolonged sleep latency, decreased sleep efficiency, decreased slow-wave and REM sleep, and fragmentation of sleep. The underlying illness and severity of acute illness, as well as the medications, standard of care, and environmental factors in the ICU can cause sleep deprivation. Improvements of patient care and environmental factors can increase the apparent sleep quality and reduce the incidence of delirium in critically ill patients.
Journal
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- Journal of the Japanese Society of Intensive Care Medicine
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Journal of the Japanese Society of Intensive Care Medicine 24 (4), 389-397, 2017
The Japanese Society of Intensive Care Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390001204445118208
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- NII Article ID
- 130005709553
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- ISSN
- 1882966X
- 13407988
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed