Non-touch, Quick Destruction of the Tracheal Occluding Balloon Using HIFU

• OSAWA Shunsuke

  Department of Surgery, Division of Pediatric Surgery, Showa University School of Medicine

• SATO Tomoo

  Port and Airport Research Institute

• YAMASHITA Hiromasa

  University Research Center, Nihon University

• MOCHIZUKI Takashi

  Medical Ultrasound Laborator

• KITAZUMI Gontaro

  Control AD Corp

• JANI Jacques

  Department of Gynecology and Obstetrics, Brugmann University Hospital

• TOKI Akira

  Department of Surgery, Division of Pediatric Surgery, Showa University School of Medicine

• CHIBA Toshio

  University Research Center, Nihon University

Abstract

The technique of fetal endoscopic tracheal occlusion (FETO) was developed to totally occlude the fetal trachea using an intratracheal balloon in the treatment of congenital diaphragmatic hernia with lung hypoplasia. To improve this approach, we developed a method for non-contact, rapid destruction of the balloon using high intensity focused ultrasound (HIFU), a specific balloon injection fluid, and euthanized rabbits (1kg). In an initial experiment (5rabbits), we inflated an intratracheal balloon by injecting in 1.0ml of fluid and demonstrated that HIFU could successfully burst the balloon in all cases, although the tracheal membranous portion and the skin overlying the trachea were injured in 4 and 2cases, respectively. In our second experiment (6animals), we inflated the balloon using only 0.5-0.6ml of fluid. In all cases, HIFU either burst (1animal) or deflated (5animals) the balloon and there was substantially decreased injury of the tracheal membranous portion (2cases) or overlying skin (2cases). The total HIFU energy output revealed no significant difference between the first and second experimental groups. In conclusion, the intratracheal balloon placed by FETO can be removed using HIFU alone.

Journal

• The Showa University Journal of Medical Sciences

  The Showa University Journal of Medical Sciences 29 (1), 87-94, 2017

  The Showa University Society

Keywords

• High Intensity Focused Ultrasound (HIFU)
• Fetal Endoscopic Tracheal Occlusion (FETO)
• Congenital Diaphragmatic Hernia (CDH)

Details

• CRID: 1390282679350188160
• NII Article ID: 130005865027
• NII Book ID: AA10781651
• DOI: 10.15369/sujms.29.87
• ISSN: 21850968
• ISSN: 09156380
• Web Site: http://id.nii.ac.jp/1670/00000521/
• Web Site: https://www.jstage.jst.go.jp/article/sujms/29/1/29_87/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018212364
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed