The Molecular Mechanisms of Ion Transportation in Microbial Rhodopsins Studied using Light-Induced Infrared Difference Spectroscopy

• Furutani Yuji

  Institute for Molecular Science

Bibliographic Information

Other Title

• 光誘起赤外差分光法による微生物型ロドプシンのイオン輸送機構の研究

Abstract

Optogenetics has been rapidly grown up since a start of pioneering works utilizing channelrhodopsin to generate action potentials of nerve cells in light dependent manner. Elucidation of molecular mechansims of microbial rhodopsins including channelrhodopsin gives guides for rational designs toward their functional alteration by genetic engineering. In this review article, the light-induced infrared difference spectroscopy is introduced as a powerful technique for investigation of light-responsive mechanisms of microbial rhodopsins.

Journal

• Nippon Laser Igakkaishi

  Nippon Laser Igakkaishi 36 (4), 460-465, 2016

  Japan Society for Laser Surgery and Medicine

Keywords

• membrane protein
• rhodopsin
• optogenetics
• infrared
• molecular vibration

Details

• CRID: 1390282679743776896
• NII Article ID: 130005966857
• DOI: 10.2530/jslsm.jslsm-36_0040
• ISSN: 18811639
• ISSN: 02886200
• Web Site: https://www.jstage.jst.go.jp/article/jslsm/36/4/36_jslsm-36_0040/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2016181131
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed