The Impact of Diabetes Mellitus on Mortality in Japanese Individuals Who Are 80 Years Old in the General Population

DOI Open Access
  • Sonoki Kazuo
    Unit for Promotion of Interdisciplinary Education and Research, School of Oral Health Science, Kyushu Dental University
  • Akifusa Sumio
    Unit of Education on Healthcare Team, School of Oral Health Science, Kyushu Dental University
  • Fukuhara Masayo
    Division of General Internal Medicine, Department of Health Promotion, Kyushu Dental University
  • Soh Inho
    Division of Community Oral Health Development, Department of Health Promotion, Kyushu Dental University
  • Awano Shuji
    Department of Clinical Education Development and Research, School of Dentistry, Kyushu Dental University
  • Ansai Toshihiro
    Division of Community Oral Health Development, Department of Health Promotion, Kyushu Dental University

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Other Title
  • 80歳一般地域住民における糖尿病の生命予後への影響

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Abstract

<p>To investigate the influence of diabetes mellitus on mortality in Japanese individuals who are 80 years old in the general population, we compared 74 diabetic subjects with 592 non-diabetic subjects who received the general and dental health examinations in Fukuoka prefecture in 1998 and who were followed-up for 4 years and 12 years after the baseline examination to collect data and information on the cause of death. The cumulative survival rate during the 12-year follow-up period from all-cause mortality and pneumonia mortality in the diabetic group was lower than that in the non-diabetic group. A Multivariate Cox regression analysis revealed that the risk of mortality in the diabetic group was higher than that in the non-diabetic group (1.76-fold for 4 years and 1.84-fold for 12 years). Notably, the risk of pneumonia mortality in the diabetic group was 3.26-fold and 2.97-fold higher than that in the non-diabetic group at 4 years and 12 years, respectively. During the 12 year follow-up period, the cancer mortality in the diabetic group was 2.42-fold higher than that in the non-diabetic group. In the poor glycemic control group, all-cause mortality at 4 years and all-cause mortality, pneumonia mortality, and cardiovascular disease mortality at 12 years were higher in comparison to the non-diabetic group. Diabetes mellitus increased the risk of mortality, especially pneumonia mortality, even in people who are 80 years old.</p>

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