ロクロニウムが原因であったアナフィラキシーショックの1例

DOI
  • 江原 雄一
    朝日大学歯学部口腔病態医療学講座口腔外科学分野
  • 住友 伸一郎
    朝日大学歯学部口腔病態医療学講座口腔外科学分野
  • 鷲見 成紀
    朝日大学歯学部口腔病態医療学講座口腔外科学分野

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  • A case of anaphylactic shock induced by rocuronium

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During operations under general anesthesia, a muscle relaxant is important to ensure airway management of endotracheal intubation and to secure a clear operation field. Rocuronium was released in October 2007. It is characterized by early effects, no accumulation and the possibility of sustained dosage, and so its usage has increased. However, a high incidence of associated anaphylaxis has been suggested. We report a case of anaphylactic shock due to administration of rocuronium during general anesthesia that was confirmed by skin test results. A 26-year-old woman was scheduled for teeth extraction under general anesthesia. She suffered an episode of anaphylactic shock with a sudden decrease in blood pressure （65/38mmHg） as the main symptom after the introduction of anesthesia and intubation. We decided to cancel the operation and gave adrenaline hydrochloride, hydrocortisone sodium succinate, ephedrine hydrochloride and so on. Her blood pressure rose and she awoke from the anesthesia. After remission, skin test results confirmed that rocuronium was the cause of the anaphylactic shock.In view of the increasing use of rocuronium, oral surgeons should consider the increased risk of anaphylaxis.

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