Detection of Periodontal Pathogens in Chorionic Tissues of Pregnant Women Diagnosed with Threatened Premature Labor and Abnormal Glucose Tolerance

• Hasegawa-Nakamura Kozue

  Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences Research and Education Center for Advanced Oral Science, Kagoshima University Graduate School of Medical and Dental Sciences

• Nakamura Toshiaki

  Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences Research and Education Center for Advanced Oral Science, Kagoshima University Graduate School of Medical and Dental Sciences

• Kamitomo Masato

  Department of Obstetrics and Gynecology, Kagoshima City Hospital

• Tateishi Fumi

  Tadashige Dental Clinic

• Hashiguchi Chikoto

  Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences Research and Education Center for Advanced Oral Science, Kagoshima University Graduate School of Medical and Dental Sciences

• Kawamata Kazuya

  Women's Hospital Aiiku

• Hatae Masayuki

  Kakinoki Hospital

• Noguchi Kazuyuki

  Department of Periodontology, Kagoshima University Graduate School of Medical and Dental Sciences Research and Education Center for Advanced Oral Science, Kagoshima University Graduate School of Medical and Dental Sciences

Bibliographic Information

Other Title

• 糖代謝異常を有する切迫早産妊婦の絨毛膜組織での歯周病原細菌の検出

Abstract

The present study aimed to investigate the association between periodontal conditions and abnormal glucose tolerance (GT) in pregnant women with threatened premature labor (TPL). Fifteen normal pregnant women, 14 women with TPL and abnormal GT (TPL/abnormal GT), and 16 women with TPL and normal GT (TPL/normal GT) were enrolled. Periodontal parameters, including probing pocket depth and clinical attachment level, were examined. Detection of Porphyromonas gingivalis (P. gingivalis), Fusobacterium nucleatum (F. nucleatum), Prevotella intermedia (P. intermedia), Aggregatibacter actinomycetemcomitans, Treponema denticola, and Tannerella forsythia (T. forsythia), in saliva, subgingival plaque, and chorionic tissues from women was performed by using polymerase chain reaction. There were no significant differences in periodontal parameters and detection rates of periodontal pathogens from oral samples between women with TPL/normal GT and TPL/abnormal GT. F. nucleatum, P. intermedia, and T. forsythia were detected in chorionic tissues of women with TPL/abnormal GT, whereas F. nucleatum and P. gingivalis were detected in chorionic tissues of those with TPL/normal GT. No periodontal pathogens were detected in the chorionic tissues of normal pregnant women. In conclusion, our data do not indicate that periodontal disease is a risk factor for abnormal GT in TPL. However, the presence of F. nucleatum, P. intermedia, and T. forsythia in chorionic tissues in women with TPL may be involved in abnormal GT.

Journal

• Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)

  Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 59 (3), 133-143, 2017

  JAPANESE SOCIETY OF PERIODONTOLOGY

Keywords

• periodontal pathogens
• abnormal glucose tolerance
• chorionic tissues
• threatened premature labor
• periodontal disease

Details

• CRID: 1390282679391008768
• NII Article ID: 130006105760
• DOI: 10.2329/perio.59.133
• ISSN: 1880408X
• ISSN: 03850110
• Web Site: https://www.jstage.jst.go.jp/article/perio/59/3/59_133/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2018017929
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed