Propensity Score Analysis in the Comparison of Long-Term Outcomes for Locally Advanced Colon Cancer Between Laparoscopic Colectomy and Open Colectomy
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- SUGIMOTO KIICHI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- SAKAMOTO KAZUHIRO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- ICHIKAWA RYOSUKE
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- KURE KAZUMASA
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- HONJO KUMPEI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- RO HISASHI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- TAKAHASHI RINA
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- KAWANO SHINGO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- NIWA KOICHIRO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- ISHIYAMA SHUN
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- KAMIYAMA HIROHIKO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- KOMIYAMA HIROMITSU
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- TAKAHASHI MAKOTO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- KOJIMA YUTAKA
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- GOTO MICHITOSHI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- OKUZAWA ATSUSHI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- ISHIBIKI YOSHIRO
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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- TOMIKI YUICHI
- Department of Coloproctological Surgery, Juntendo University Faculty of Medicine
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Abstract
<p>Objective: It is difficult to conduct a randomised control trial in a single institution because of the small number of cases. The current study was conducted to investigate if there is any difference in long-term outcome between laparoscopic surgery (LAC) and open surgery (OC) using propensity-score matching analysis based on prognostic factors.</p><p>Materials: Two hundred and sixteen patients with locally-advanced colon cancer who underwent surgery with curative intent at our department between 2002 and 2010 were enrolled in the current study.</p><p>Methods: Propensity score matching analysis and Inverse Probability Weighting (IPW) estimator were used to adjust for differences in the clinicopathological severity between LAC and OC.</p><p>Results: Before propensity score matching analysis recurrence-free survival in LAC was statistically better than that in OC (Hazard ratio= 0.59, 95% CI 0.35-0.98, p=0.04), and no statistically significant difference was recognized for cancer-specific survival (Hazard ratio=0.63, 95% CI 0.27-1.37, p=0.25). After propensity score matching analysis there were no statistically significant differences for recurrence-free (Hazard ratio=0.91, 95% CI 0.41-2.01, p=0.81) or cancer-specific survival (Hazard ratio=1.38, 95% CI 0.41-4.82, p=0.59). In addition, the IPW estimator revealed that the difference for recurrence-free survival was not significant between the two groups.</p><p>Conclusion: The one-to-one pair propensity score matching successfully balanced the clinicopathological factors between LAC and OC. The propensity score matching analysis demonstrated no significant difference between LAC and OC.</p>
Journal
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- Juntendo Medical Journal
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Juntendo Medical Journal 63 (4), 264-272, 2017
The Juntendo Medical Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001205517484800
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- NII Article ID
- 130006106309
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- NII Book ID
- AA1262207X
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- ISSN
- 21882126
- 21879737
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- NDL BIB ID
- 028604892
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed