Revealing the genomic differences between two subgroups in <i>Lactobacillus gasseri</i>

Access this Article

Search this Article

Author(s)

    • TADA Ipputa
    • Department of Genetics, School of Life Science, The Graduate University of Advanced Studies, Mishima, Shizuoka 411-8540, Japan
    • TANIZAWA Yasuhiro
    • Center for Information Biology, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan
    • ENDO Akihito
    • Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, Abashiri, Hokkaido 099-2493, Japan
    • TOHNO Masanori
    • National Agriculture and Food Research Organization, National Institute of Livestock and Grassland Science, Tochigi 329-2793, Japan
    • ARITA Masanori
    • Center for Information Biology, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan|RIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa 230-0045, Japan

Abstract

<p>Being an autochthonous species in humans, <i>Lactobacillus gasseri</i> is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 <i>L. gasseri</i> genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48 strains, possessed 53 group-specific genes including the gassericin T cluster (9 genes) and <i>N</i>-acyl homoserine lactone lactonase. Group II, with 27 strains, including the type strain ATCC 33323, possessed group-specific genes with plasmid- or phage-related annotations. The genomic differences provide evidences for demarcating a new probiotic group within <i>L. gasseri.</i></p>

Journal

  • Bioscience of Microbiota, Food and Health

    Bioscience of Microbiota, Food and Health 36(4), 155-159, 2017

    BMFH Press

Codes

Page Top