Development of the gut microbiota in infancy and its impact on health in later life

• Tanaka Masaru

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

• Nakayama Jiro

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Abstract

Gut microbial ecology and function are dynamic in infancy, but are stabilized in childhood. The ‘new friends’ have a great impact on the development of the digestive tract and host immune system. In the first year of life, especially, the gut microbiota dramatically changes through interactions with the developing immune system in the gut. The process of establishing the gut microbiota is affected by various environmental factors, with the potential to be a main determinant of life-long health. In this review, we summarize recent findings regarding gut microbiota establishment, including the importance of various factors related to the development of the immune system and allergic diseases later in life.

Journal

• Allergology International

  Allergology International 66 (4), 515-522, 2017

  Japanese Society of Allergology

Keywords

• Allergy
• Bifidobacterium
• Gut microbiota
• Hygiene hypothesis
• Infants

Details

• CRID: 1390282679609597056
• NII Article ID: 130006179523
• DOI: 10.1016/j.alit.2017.07.010
• ISSN: 14401592
• ISSN: 13238930
• Web Site: https://api.elsevier.com/content/article/PII:S1323893017301119?httpAccept=text/xml
• Web Site: https://api.elsevier.com/content/article/PII:S1323893017301119?httpAccept=text/plain
• Web Site: https://search.jamas.or.jp/link/ui/2018302398
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed