Morning and Evening Blood Pressures Are Associated With Intima-Media Thickness in a General Population ― The Hisayama Study ―

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Author(s)

    • Sakata Satoko Sakata Satoko
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
    • Fukuhara Masayo Ninomiya Toshiharu
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University
    • Yonemoto Koji Hata Jun
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University|Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
    • Kishimoto Hiro Mukai Naoko
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University|Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
    • Ohtsubo Toshio Yoshida Daigo
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University
    • Kitazono Takanari Kishimoto Hiro
    • Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University|Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University
    • Ninomiya Toshiharu Kitazono Takanari
    • Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University|Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University

Abstract

<p><b><i>Background:</i></b>The association of morning and evening home blood pressures (HBPs) with carotid atherosclerosis has been uncertain in general populations, so we aimed to investigate it in a general Japanese population.</p><p><b><i>Methods and Results:</i></b>We performed a cross-sectional survey of 2,856 community-dwelling individuals aged ≥40 years to examine the association of morning and evening HBPs with carotid mean intima-media thickness (IMT). The age- and sex-adjusted geometric averages of carotid mean IMT increased significantly with increasing morning HBP (optimal: 0.67 mm; normal: 0.69 mm; high normal: 0.72 mm; grade 1 hypertension: 0.74 mm; and grade 2+3 hypertension: 0.76 mm) and with increasing evening HBP (0.68 mm, 0.71 mm, 0.73 mm, 0.76 mm, and 0.78 mm, respectively) (both P for trend <0.001). These associations remained significant even after adjusting for potential confounding factors. Likewise, both isolated morning hypertension (morning HBP ≥135/85 mmHg and evening HBP <135/85 mmHg) and isolated evening hypertension (evening HBP ≥135/85 mmHg and morning HBP <135/85 mmHg) as well as sustained hypertension (both morning and evening HBP ≥135/85 mmHg) were significantly associated with thicker mean IMT.</p><p><b><i>Conclusions:</i></b>Our findings suggested that both morning and evening HBPs were significantly associated with carotid atherosclerosis in this general Japanese population.</p>

Journal

  • Circulation Journal

    Circulation Journal 81(11), 1647-1653, 2017

    The Japanese Circulation Society

Codes

  • NII Article ID (NAID)
    130006179861
  • NII NACSIS-CAT ID (NCID)
    AA11591968
  • Text Lang
    ENG
  • ISSN
    1346-9843
  • NDL Article ID
    028596480
  • NDL Call No.
    Z54-B860
  • Data Source
    NDL  J-STAGE 
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