Evaluation of the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay

  • Maruki-Uchida Hiroko
    Research and Development Department, Health and Wellness Headquarters, Morinaga and Company Limited
  • Sai Masahiko
    Research and Development Department, Health and Wellness Headquarters, Morinaga and Company Limited
  • Sekimizu Kazuhisa
    Institute of Medical Mycology, Teikyo University Genome Pharmaceuticals Institute Co., Ltd.

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<p>We evaluated the innate immune-stimulating activity of amazake using a silkworm muscle contraction assay. Sake cake, a raw material used to make amazake, had high innate immunity-stimulating activity, whereas rice malt, another raw material used to make amazake, did not, even after fermentation. These results suggest that the silkworm muscle contraction assay is a useful tool to screen foods with high innate immune-stimulating activity and that amazake made from sake cake has immunomodulatory potential.</p>

収録刊行物

  • Drug Discoveries & Therapeutics

    Drug Discoveries & Therapeutics 11 (5), 288-290, 2017

    特定非営利活動法人 バイオ&ソーシャル・サイエンス推進国際研究交流会

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