Cyclodextrin–Grafted Chitosans for Pharmaceutical Applications

• Izawa Hironori

  Graduate School of Engineering, Tottori University

• Takechi Haraya Yuki

  Division of Drugs, National Institute of Health Sciences

• Kawakami Kohsaku

  World Premier International (WPI) Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS)

Abstract

Rationally designed artificial polysaccharides have interesting functions that natural polysaccharides lack. Recently, we found that β-cyclodextrin–grafted chitosan formed supramolecular aggregates that showed interesting functions, leading to pharmaceutical applications such as the enhancement of intentional absorption of insulin and cholesterol efflux from cells. Here we introduce our works concerning cyclodextrin-grafted chitosan for pharmaceutical application.

Journal

• Trends in Glycoscience and Glycotechnology

  Trends in Glycoscience and Glycotechnology 29 (170), E93-E98, 2017

  FCCA(Forum: Carbohydrates Coming of Age)

Keywords

• cyclodextrin
• chitosan
• drug delivery system
• supramolecular aggregates
• protein

Details

• CRID: 1390001204369373696
• NII Article ID: 40021579308
• NII Article ID: 130006219357
• NII Book ID: AA10995236
• DOI: 10.4052/tigg.1620.1e
• ISSN: 18832113
• ISSN: 09157352
• NDL BIB ID: 029070371
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I029070371
• Web Site: https://www.jstage.jst.go.jp/article/tigg/29/170/29_1620.1E/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed