Highlighted Paper selected by Editor-in-Chief : Synthesis of Tetrahydrobiphenylene via Pd(0)-Catalyzed C(sp²)-H Functionalization

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  • Synthesis of Tetrahydrobiphenylene <i>via</i> Pd(0)-Catalyzed C(<i>sp</i><sup>2</sup>)–H Functionalization

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<p>Tetrahydrobiphenylene consists of cyclobutene fused with benzene and cyclohexene rings. In this paper, a direct method for synthesizing tetrahydrobiphenylenes based on a palladium (Pd)(0)-catalyzed C(sp2)–H functionalization was investigated. The developed method was applied to the synthesis of several tetrahydrobiphenylenes having an oxygen functionality at the ring juncture. The derivatization of a tetrahydrobiphenylene is also reported.</p>

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